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Table 2 Prognostic factors for overall survival and recurrence-free survival by the univariate Cox proportional hazards regression model

From: NCSTN promotes hepatocellular carcinoma cell growth and metastasis via β-catenin activation in a Notch1/AKT dependent manner

Variables

Overall survival

Recurrence-free survival

HR

95% CI

P

HR

95% CI

P

Age

0.998

0.979–1.018

0.872

0.998

0.984–1.013

0.807

Gender (F/M)

0.922

0.481–1.769

0.807

0.920

0.574–1.475

0.729

HBsAg

1.581

0.908–2.753

0.105

1.394

0.798–2.437

0.243

AFP (≥400/< 400)

1.335

0.943–1.891

0.104

1.799

1.252–2.586

0.001

Ascites (+/−)

1.057

0.451–1.986

0.884

1.693

1.025–2.797

0.040

Tumor size (> 5/≤5)

1.755

1.246–2.530

0.002

1.440

0.998–2.077

0.051

Multiple tumors

1.754

1.161–2.652

0.008

1.734

1.114–2.698

0.015

Differentiation (Poor/Well-Moderate)

1.188

0.842–1.678

0.327

1.081

0.751–1.560

0.671

TNM stage (III/I-II)

1.325

0.902–1.946

0.151

1.456

0.973–2.177

0.067

Macrovascular invasion

3.039

1.408–6.556

0.005

2.739

1.268–5.915

0.010

Microvascular invasion

2.621

1.846–3.721

0.001

2.337

1.621–3.369

0.001

Cirrhosis

1.191

0.832–1.707

0.339

1.174

0.803–1.715

0.407

NCSTN (high/low)

1.721

1.203–2.460

0.003

1.566

1.080–2.272

0.017

  1. TNM Tumor-node-metastasis, HR Hazard ratio, CI Confidence interval, F Female, M Male