Fig. 7

CircNTRK2 silencing inhibited tumor formation in xenografted nude mice. (a-e) KYSE-150 cells stably transfected with sh-circNTRK2 were implanted into nude mice. (a) The growth curve of xenograft tumors was shown. (b) Tumor weight measurement in sh-NC- or sh-circNTRK2-treated nude mice, and representative images of excised tumor masses. (c-d) The levels of circNTRK2 and miR-140-3p were examined in tumors via qRT-PCR. (e) The protein levels of NRIP1 were tested in xenografts by western blot assay. *P < 0.05, **P < 0.01