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Fig. 6 | Journal of Experimental & Clinical Cancer Research

Fig. 6

From: Hypoxia induced ferritin light chain (FTL) promoted epithelia mesenchymal transition and chemoresistance of glioma

Fig. 6

FTL is a novel biomarker of response to TMZ in glioma. a-b Kaplan-Meier overall survival curves in TCGA-GBM patients. Patient were divided into groups according to median FTL expression and treatment modality (TMZ at any time vs IR only). c-dTCGA-LGG patients were separated by median FTL expression and treatment modality (TMZ at any time vs IR only).e Correlation between FTL and MGMT in TCGA,CGGA and Rembrandt datasets. Pearson test was used for correlation analysis. f Relationship between FTL expression and MGMT status in TCGA-GBMLGG.g-h Patient were divided into groups according to median FTL expression and different methylation status of MGMT promoter in TCGA-GBM and TCGA-LGG. ***, P < 0.001

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