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Table 1 Univariate analysis and multivariate COX analysis of clinical prognostic parameters in TCGA dataset

From: Hypoxia induced ferritin light chain (FTL) promoted epithelia mesenchymal transition and chemoresistance of glioma

Variables

Univariate Cox regression

Multivariate Cox regression

HR(95%CI)

P value

HR(95%CI)

P value

Age

(≥55y vs<55y)

5.27(3.95–7.03)

< 0.001

2.05(1.49–2.84)

< 0.001

Gender

(Female vs male)

0.85(0.64–1.11)

0.23

WHO Grade

(high vs low)

5.43(.68–8.04)

< 0.001

2.23(1.45–3.42)

< 0.001

IDH status

(Wildtype vs mutant)

10.58(7.77–14.41)

< 0.001

5.17(3.54–7.55)

< 0.001

FTL expression

(High vs Low)

2.87(2.15–3.83)

< 0.001

1.44(1.06–1.95)

0.02

  1. TCGA, the cancer genome atlas;WHO,World Health Organization;IDH, Isocitrate dehydrogenase;HR,hazard ration