Table 1 Characteristics of lung cancer patients and healthy controls
Variables | Control | NSCLC | P value | OR value | P value | OR value* |
|---|---|---|---|---|---|---|
N = 1509 | N = 1198 | |||||
Age at dx (year) | < 0.001 | < 0.001 | ||||
< 60 | 1203 (79.72%) | 604 (50.42%) | 1 | 1 | ||
≥ 60 | 306 (20.28%) | 594 (49.58%) | 3.87 (3.27–4.58) | 3.20 (2.68–3.82) | ||
Gender | < 0.001 | 0.82 | ||||
male | 422 (27.97%) | 544 (45.41%) | 1 | 1 | ||
female | 1087 (72.03%) | 654 (54.59%) | 0.47 (0.40–0.55) | 0.98 (0.80–1.20) | ||
Smoking status | < 0.001 | < 0.001 | ||||
no | 1293 (85.69%) | 665 (55.60%) | 1 | 1 | ||
yes | 216 (14.31%) | 531 (44.40%) | 4.78 (3.98–5.74) | 3.89 (3.11–4.87) | ||
SNP rs140618127 | 0.007 | 0.018 | ||||
G allele | 1476 (97.81%) | 1188 (99.17%) | 1 | 1 | ||
A allele | 33 (2.19%) | 10 (0.83%) | 0.38 (0.19–0.77) | 0.40 (0.18–0.86) |