Fig. 6

Rap1b inhibition restrained the tumorigenesis effects of LINC00514. (a-b) CCK-8 assay was performed to detect proliferation of cells transfected with LINC00514 overexpression plasmids and cells co-transfected with LINC00514 overexpression plasmids and Rap1b shRNA. (c-d) Transwell migration and invasion assay were carried out to detect cell migration and invasion abilities. *p<.05, **p<.01, **p<.001. All experiments were repeated at least for three times and mean±SD was used to represent the final result. PC, pancreatic cancer; qRT-PCR, quantitative real-time polymerase chain reaction; SD, standard deviation; CCK-8, cell counting kit-8