Fig. 3
From: Comprehensive analysis of the mechanism and treatment significance of Mucins in lung cancer
Schematic diagram of signaling pathways other mucins involved in non-small cell lung cancer. MUC5AC implicated in activating FAK and AKT pathways. MUC4 promote the proliferation and metastasis of lung cancer through regulation cell cycle related genes and EMT. MUC16 regulated the transcription of TSPYL5 via JAK/STAT3 and P53 pathways. Moreover, EGFR regulated the MUC2/5 AC expression through ERK pathway