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Fig. 7 | Journal of Experimental & Clinical Cancer Research

Fig. 7

From: Long noncoding RNA ZFPM2-AS1 acts as a miRNA sponge and promotes cell invasion through regulation of miR-139/GDF10 in hepatocellular carcinoma

Fig. 7

miR-139 mimics and si-GDF10 reversed the promoting function of lncRNA ZFPM2-AS1 in vitro. a CCK-8 assay of Huh7 cells transfected with miR-139, siGDF10, pcDNA/ZFPM2-AS1 and miR-139 + siGDF10 + pcDNA/ZFPM2-AS1at 0 h, 24 h, 48 h and 72 h to measure cell viability. b Flow cytometry was used to detect the cell apoptosis of miR-139-, siGDF10-, pcDNA/ZFPM2-AS1- and miR-139+ siGDF10+ pcDNA/ZFPM2-AS1-transfected Huh7 cells. c Transwell chamber assay was used to detect the migration and invasion ability of miR-139-, siGDF10-, pcDNA/ZFPM2-AS1- and miR-139+ siGDF10+ pcDNA/ZFPM2-AS1-transfected Huh7 cells. The right side is a statistical graph of the migrating cell count and the invasive cell count, respectively. The data are expressed as the mean ± standard deviation, **P < 0.01, ***P < 0.001(vs miR-139)

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