Fig. 1

miR-216b expression is decreased in OS and its high expression is positively correlated with patient survival. a miR-216b expression was determined by RT-qPCR in OS and paracancerous tissues from patients (n = 60), relative to U6. * p < 0.05 vs. paracancerous tissues by paired t-test. b Overall survival in OS patients was determined by the Kaplan-Meier method. c miR-216b expression was determined by RT-qPCR in OS cell lines and normal hFOB1.19 cell line, relative to U6. * p < 0.05 vs. hFOB1.19 cell line by one-way ANOVA, followed by Tukey’s test. Data in panel (b) were compared with unpaired t-test. Data are shown as mean ± standard deviation of three technical replicates