Fig. 2

miR-216b enhances cisplatin-induced apoptosis in OS cells. a Cell viability in MG63 and SaOS-2 cells was determined by CCK-8 assay upon treatment with miR-216b agomir. b Apoptosis of MG63 cells was determined by flow cytometry upon treatment with miR-216b agomir. c Apoptosis of SaOS-2 cells was determined by flow cytometry upon treatment with miR-216b agomir. * p < 0.05 vs. cells treated with agomir NC. Data in panel (a) and (c) were compared by unpaired t-test while data in panel (b) were compared by repeated measures ANOVA with Bonferroni test. Data are shown as mean ± standard deviation of three technical replicates