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Fig. 1 | Journal of Experimental & Clinical Cancer Research

Fig. 1

From: CREB5 promotes invasiveness and metastasis in colorectal cancer by directly activating MET

Fig. 1

CREB5 is upregulated in CRC and associated with a poor prognosis. a and b Real-time PCR and western blotting analysis of CREB5 expression in paired human colon cancer tissues and adjacent noncancerous tissues (p < 0.01). Quantity One software was used to quantify the protein expression levels. c IHC representative images of CREB5 expression in normal intestinal epithelium and CRC tissues. Scale bar: 50 μm. d The paraffin samples of 198 CRC patients were divided into a low-CREB5 expression group (n = 108) and a high-CREB5 expression group (n = 90) based on IHC results. The Kaplan-Meier method was used to analyse survival curves, and the log-rank test was used to compare differences (p = 0.023)

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