Fig. 1

Aberrant expression of LINC00669 in NPC tumors and cells. a, Venn diagram showing 152 common lncRNA signatures that are upregulated in NPC mRNA expression profiling databases of GSE12452 [14] and GSE53819 [15]. b, Microarray data showing upregulation of LINC00669 in NPC tumors. c, Kaplan-Meier analysis showing a negative correlation of the overall survival rate of NPC patients with LINC00669 level. d, qPCR analysis showing an upregulation of LINC00669 in the clinical NPC tumor samples. ** p < 0.01. e, qPCR analysis showing a general upregulation of LINC00669 in different NPC cell lines. f, FISH analysis showing cytoplasmic localization of LINC00669 in NPC cells. DAPI was used for nuclear counterstaining. U6 was used as a positive control for nuclear localization