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Fig. 6 | Journal of Experimental & Clinical Cancer Research

Fig. 6

From: LINC00669 insulates the JAK/STAT suppressor SOCS1 to promote nasopharyngeal cancer cell proliferation and invasion

Fig. 6

LINC00669 stabilizes STAT1 and facilitates its nuclear translocation. a, Western blotting showing the decreased STAT1 protein stability in the absence of LINC00669 in NPC cells. NC, negative control; siLINC, siRNA-mediated silencing of LINC00669; CHX, cycloheximide. b, Western blotting showing phosphorylation (Y701) of STAT1 was greatly enhanced upon ectopic expression of LINC00669. c, Immunofluorescence assay showing the increased nuclear translocation of STAT1 in the LINC00669-everexpressing NPC cells

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