Fig. 6From: LINC00669 insulates the JAK/STAT suppressor SOCS1 to promote nasopharyngeal cancer cell proliferation and invasionLINC00669 stabilizes STAT1 and facilitates its nuclear translocation. a, Western blotting showing the decreased STAT1 protein stability in the absence of LINC00669 in NPC cells. NC, negative control; siLINC, siRNA-mediated silencing of LINC00669; CHX, cycloheximide. b, Western blotting showing phosphorylation (Y701) of STAT1 was greatly enhanced upon ectopic expression of LINC00669. c, Immunofluorescence assay showing the increased nuclear translocation of STAT1 in the LINC00669-everexpressing NPC cellsBack to article page