TY - JOUR AU - Guo, Pin AU - Tian, Zibin AU - Kong, Xinjuan AU - Yang, Lin AU - Shan, Xinzhi AU - Dong, Bingzi AU - Ding, Xueli AU - Jing, Xue AU - Jiang, Chen AU - Jiang, Na AU - Yu, Yanan PY - 2020 DA - 2020/09/29 TI - FadA promotes DNA damage and progression of Fusobacterium nucleatum-induced colorectal cancer through up-regulation of chk2 JO - Journal of Experimental & Clinical Cancer Research SP - 202 VL - 39 IS - 1 AB - Globally, colorectal cancer (CRC) affects more than 1 million people each year. In addition to non-modifiable and other environmental risk factors, Fusobacterium nucleatum infection has been linked to CRC recently. In this study, we explored mechanisms underlying the role of Fusobacterium nucleatum infection in the progression of CRC in a mouse model. SN - 1756-9966 UR - https://doi.org/10.1186/s13046-020-01677-w DO - 10.1186/s13046-020-01677-w ID - Guo2020 ER -