CircRNA hsa_circ_0002577 accelerates endometrial cancer progression through activating IGF1R/PI3K/Akt pathway

Table 1 Relationship between hsa_circ_0002577 and clinico-pathological parameters

Parameters	Number of patients	hsa_circ_0002577 expression		Positive rate (%)	P value
Parameters	Number of patients	Low (< median)	High (≥ median)	Positive rate (%)	P value
Number	84	42	42
Age (years)
≥ Mean (55)	58	28	30	69	0.637
< Mean (55)	26	14	12	31	0.637
FIGO stage
I-II	63	37	26	75	0.006**
III-IV	21	5	16	25	0.006**
Pathological type
Endometrioid	68	36	32	81	0.266
Non-endometrioid	16	6	10	19	0.266
Histological grade
Grade 1	45	30	15	54	0.002**
Grade 2	27	10	17	32
Grade 3	12	2	10	14
LNM
Positive	22	5	17	26	0.003**
Negative	62	37	25	74	0.003**
LVS
Positive	26	6	20	31	0.001**
Negative	58	36	22	69	0.001**
Depth of myometrial invasion
≤ 1/2	69	37	32	82	0.154
> 1/2	15	5	10	18	0.154
ER expression
Positive	19	7	12	23	0.192
Negative	65	35	30	77	0.192
FR expression
Positive	21	7	14	25	0.078
Negative	63	35	28	75	0.078

ISSN: 1756-9966