Fig. 3
PMSB8-AS1 promotes growth and metastasis of pancreatic cancer in vivo. a Nude mice were given xenografts of PSMB8-AS1 overexpressed and knockdown PANC-1 cells (5 × 106 cells per site). The tumors were dissected and photographed after approximately six weeks (n = 5 per group). b The growth curve of PSMB8-AS1 overexpressed and knockdown tumors compared to the control group. c The IHC was performed to analyze the KI-67 and PCNA in the PSMB8-AS1 overexpressed and knockdown xenograft tissues. d Representative images of the liver of PSMB8-AS1 with overexpressed and knockdown tumors compared to the control group. e Representative images of HE staining in metastatic nodules in the lungs of nude mice. The metastatic nodules are indicated by red line