TY - JOUR AU - Ben, Qiwen AU - An, Wei AU - Sun, Yunwei AU - Qian, Aihua AU - Liu, Jun AU - Zou, Duowu AU - Yuan, Yaozong PY - 2020 DA - 2020/09/07 TI - A nicotine-induced positive feedback loop between HIF1A and YAP1 contributes to epithelial-to-mesenchymal transition in pancreatic ductal adenocarcinoma JO - Journal of Experimental & Clinical Cancer Research SP - 181 VL - 39 IS - 1 AB - Nicotine, an active ingredient in tobacco, can promote epithelial-to-mesenchymal transition (EMT) processes that enhance the aggressiveness of a number of human cancers. In the present study, we investigated whether cigarette smoke/nicotine drives EMT in pancreatic ductal adenocarcinoma (PDAC). SN - 1756-9966 UR - https://doi.org/10.1186/s13046-020-01689-6 DO - 10.1186/s13046-020-01689-6 ID - Ben2020 ER -