TY - JOUR AU - Bray, F. AU - Ferlay, J. AU - Soerjomataram, I. AU - Siegel, R. L. AU - Torre, L. A. AU - Jemal, A. PY - 2018 DA - 2018// TI - Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries JO - CA Cancer J Clin VL - 68 ID - Bray2018 ER - TY - JOUR AU - Strobel, O. AU - Neoptolemos, J. AU - Jager, D. AU - Buchler, M. W. PY - 2019 DA - 2019// TI - Optimizing the outcomes of pancreatic cancer surgery JO - Nat Rev Clin Oncol VL - 16 ID - Strobel2019 ER - TY - JOUR AU - Maisonneuve, P. AU - Lowenfels, A. B. PY - 2015 DA - 2015// TI - Risk factors for pancreatic cancer: a summary review of meta-analytical studies JO - Int J Epidemiol VL - 44 ID - Maisonneuve2015 ER - TY - JOUR AU - Ben, Q. W. AU - Liu, J. AU - Sun, Y. W. AU - Wang, L. F. AU - Zou, D. W. AU - Yuan, Y. Z. PY - 2019 DA - 2019// TI - Cigarette smoking and mortality in patients with pancreatic Cancer: a systematic review and meta-analysis JO - Pancreas VL - 48 ID - Ben2019 ER - TY - JOUR AU - Delitto, D. AU - Zhang, D. AU - Han, S. AU - Black, B. S. AU - Knowlton, A. E. AU - Vlada, A. C. PY - 2016 DA - 2016// TI - Nicotine reduces survival via augmentation of paracrine HGF-MET signaling in the pancreatic Cancer microenvironment JO - Clin Cancer Res VL - 22 ID - Delitto2016 ER - TY - JOUR AU - Hermann, P. C. AU - Sancho, P. AU - Canamero, M. AU - Martinelli, P. AU - Madriles, F. AU - Michl, P. PY - 2014 DA - 2014// TI - Nicotine promotes initiation and progression of KRAS-induced pancreatic cancer via Gata6-dependent dedifferentiation of acinar cells in mice JO - Gastroenterology VL - 147 ID - Hermann2014 ER - TY - JOUR AU - Nimmakayala, R. K. AU - Seshacharyulu, P. AU - Lakshmanan, I. AU - Rachagani, S. AU - Chugh, S. AU - Karmakar, S. PY - 2018 DA - 2018// TI - Cigarette smoke induces stem cell features of pancreatic Cancer cells via PAF1 JO - Gastroenterology VL - 155 ID - Nimmakayala2018 ER - TY - JOUR AU - Lamouille, S. AU - Xu, J. AU - Derynck, R. PY - 2014 DA - 2014// TI - Molecular mechanisms of epithelial-mesenchymal transition JO - Nat Rev Mol Cell Biol VL - 15 ID - Lamouille2014 ER - TY - JOUR AU - Nieto, M. A. AU - Huang, R. Y. AU - Jackson, R. A. AU - Thiery, J. P. PY - 2016 DA - 2016// TI - Emt: 2016 JO - Cell VL - 166 ID - Nieto2016 ER - TY - JOUR AU - Dongre, A. AU - Weinberg, R. A. PY - 2019 DA - 2019// TI - New insights into the mechanisms of epithelial-mesenchymal transition and implications for cancer JO - Nat Rev Mol Cell Biol VL - 20 ID - Dongre2019 ER - TY - JOUR AU - Zhang, N. AU - Zhu, T. AU - Yu, K. AU - Shi, M. AU - Wang, X. AU - Wang, L. PY - 2019 DA - 2019// TI - Elevation of O-GlcNAc and GFAT expression by nicotine exposure promotes epithelial-mesenchymal transition and invasion in breast cancer cells JO - Cell Death Dis VL - 10 ID - Zhang2019 ER - TY - STD TI - Vu T, Jin L, Datta PK. Effect of cigarette smoking on epithelial to Mesenchymal transition (EMT) in lung Cancer. J Clin Med. 2016;5:44. ID - ref12 ER - TY - JOUR AU - Zhang, L. AU - Song, X. AU - Li, X. AU - Wu, C. AU - Jiang, J. PY - 2018 DA - 2018// TI - Yes-associated protein 1 as a novel prognostic biomarker for gastrointestinal Cancer: a meta-analysis JO - Biomed Res Int VL - 2018 ID - Zhang2018 ER - TY - STD TI - Yoo W, Lee J, Jun E, Noh KH, Lee S, Jung D, et al. The YAP1-NMU Axis is associated with pancreatic Cancer progression and poor outcome: identification of a novel diagnostic biomarker and therapeutic target. Cancers (Basel). 2019;11:1477. ID - ref14 ER - TY - JOUR AU - Zhang, J. AU - Ji, J. Y. AU - Yu, M. AU - Overholtzer, M. AU - Smolen, G. A. AU - Wang, R. PY - 2009 DA - 2009// TI - YAP-dependent induction of amphiregulin identifies a non-cell-autonomous component of the hippo pathway JO - Nat Cell Biol VL - 11 ID - Zhang2009 ER - TY - JOUR AU - Rozengurt, E. AU - Sinnett-Smith, J. AU - Eibl, G. PY - 2018 DA - 2018// TI - Yes-associated protein (YAP) in pancreatic cancer: at the epicenter of a targetable signaling network associated with patient survival JO - Signal Transduct Target Ther VL - 3 ID - Rozengurt2018 ER - TY - JOUR AU - Fang, L. AU - Teng, H. AU - Wang, Y. AU - Liao, G. AU - Weng, L. AU - Li, Y. PY - 2018 DA - 2018// TI - SET1A-mediated mono-methylation at K342 regulates YAP activation by blocking its nuclear export and promotes tumorigenesis JO - Cancer Cell VL - 34 ID - Fang2018 ER - TY - JOUR AU - Zhao, Y. AU - Zhou, W. AU - Xue, L. AU - Zhang, W. AU - Zhan, Q. PY - 2014 DA - 2014// TI - Nicotine activates YAP1 through nAChRs mediated signaling in esophageal squamous cell cancer (ESCC) JO - PLoS One VL - 9 ID - Zhao2014 ER - TY - JOUR AU - Schaal, C. M. AU - Bora-Singhal, N. AU - Kumar, D. M. AU - Chellappan, S. P. PY - 2018 DA - 2018// TI - Regulation of Sox2 and stemness by nicotine and electronic-cigarettes in non-small cell lung cancer JO - Mol Cancer VL - 17 ID - Schaal2018 ER - TY - STD TI - Butturini E. Carcereri de Prati a, Boriero D, Mariotto S. Tumor dormancy and interplay with hypoxic tumor microenvironment. Int J Mol Sci. 2019;20:4305. ID - ref20 ER - TY - JOUR AU - Schito, L. PY - 2018 DA - 2018// TI - Bridging angiogenesis and immune evasion in the hypoxic tumor microenvironment JO - Am J Phys Regul Integr Comp Phys VL - 315 ID - Schito2018 ER - TY - JOUR AU - Shi, D. AU - Guo, W. AU - Chen, W. AU - Fu, L. AU - Wang, J. AU - Tian, Y. PY - 2012 DA - 2012// TI - Nicotine promotes proliferation of human nasopharyngeal carcinoma cells by regulating alpha7AChR, ERK, HIF-1alpha and VEGF/PEDF signaling JO - PLoS One VL - 7 ID - Shi2012 ER - TY - JOUR AU - Daijo, H. AU - Hoshino, Y. AU - Kai, S. AU - Suzuki, K. AU - Nishi, K. AU - Matsuo, Y. PY - 2016 DA - 2016// TI - Cigarette smoke reversibly activates hypoxia-inducible factor 1 in a reactive oxygen species-dependent manner JO - Sci Rep VL - 6 ID - Daijo2016 ER - TY - BOOK PY - 2010 DA - 2010// TI - AJCC Cancer Staging Handbook PB - Springer CY - New York ID - ref24 ER - TY - JOUR AU - Bachmann, I. M. AU - Halvorsen, O. J. AU - Collett, K. AU - Stefansson, I. M. AU - Straume, O. AU - Haukaas, S. A. PY - 2006 DA - 2006// TI - EZH2 expression is associated with high proliferation rate and aggressive tumor subgroups in cutaneous melanoma and cancers of the endometrium, prostate, and breast JO - J Clin Oncol VL - 24 ID - Bachmann2006 ER - TY - JOUR AU - Xu, X. AU - Han, K. AU - Tang, X. AU - Zeng, Y. AU - Lin, X. AU - Zhao, Y. PY - 2016 DA - 2016// TI - The ring finger protein RNF6 induces leukemia cell proliferation as a direct target of pre-B-cell leukemia Homeobox 1 JO - J Biol Chem VL - 291 ID - Xu2016 ER - TY - JOUR AU - Ross, J. AU - Bottardi, S. AU - Bourgoin, V. AU - Wollenschlaeger, A. AU - Drobetsky, E. AU - Trudel, M. PY - 2009 DA - 2009// TI - Differential requirement of a distal regulatory region for pre-initiation complex formation at globin gene promoters JO - Nucleic Acids Res VL - 37 ID - Ross2009 ER - TY - JOUR AU - Tang, Z. AU - Li, C. AU - Kang, B. AU - Gao, G. AU - Li, C. AU - Zhang, Z. PY - 2017 DA - 2017// TI - GEPIA: a web server for cancer and normal gene expression profiling and interactive analyses JO - Nucleic Acids Res VL - 45 ID - Tang2017 ER - TY - JOUR AU - Li, J. H. AU - Liu, S. AU - Zhou, H. AU - Qu, L. H. AU - Yang, J. H. PY - 2014 DA - 2014// TI - starBase v2.0: decoding miRNA-ceRNA, miRNA-ncRNA and protein-RNA interaction networks from large-scale CLIP-Seq data JO - Nucleic Acids Res VL - 42 ID - Li2014 ER - TY - STD TI - Ben Q, Sun Y, Liu J, Wang W, Zou D, Yuan Y. Nicotine promotes tumor progression and epithelial-mesenchymal transition by regulating the miR-155-5p/NDFIP1 axis in pancreatic ductal adenocarcinoma. Pancreatology. 2020;20:698–708. ID - ref30 ER - TY - JOUR AU - Zanconato, F. AU - Cordenonsi, M. AU - Piccolo, S. PY - 2016 DA - 2016// TI - YAP/TAZ at the roots of Cancer JO - Cancer Cell VL - 29 ID - Zanconato2016 ER - TY - JOUR AU - Schaal, C. AU - Padmanabhan, J. AU - Chellappan, S. PY - 2015 DA - 2015// TI - The role of nAChR and calcium signaling in pancreatic Cancer initiation and progression JO - Cancers (Basel) VL - 7 ID - Schaal2015 ER - TY - JOUR AU - Al-Wadei, M. H. AU - Al-Wadei, H. A. AU - Schuller, H. M. PY - 2012 DA - 2012// TI - Pancreatic cancer cells and normal pancreatic duct epithelial cells express an autocrine catecholamine loop that is activated by nicotinic acetylcholine receptors alpha3, alpha5, and alpha7 JO - Mol Cancer Res VL - 10 ID - Al-Wadei2012 ER - TY - JOUR AU - Huang, C. AU - Li, Y. AU - Li, Z. AU - Xu, Y. AU - Li, N. AU - Ge, Y. PY - 2019 DA - 2019// TI - LIMS1 promotes pancreatic Cancer cell survival under oxygen-glucose deprivation conditions by enhancing HIF1A protein translation JO - Clin Cancer Res VL - 25 ID - Huang2019 ER - TY - JOUR AU - Wang, S. AU - Huang, S. AU - Sun, Y. L. PY - 2017 DA - 2017// TI - Epithelial-Mesenchymal transition in pancreatic Cancer: a review JO - Biomed Res Int VL - 2017 ID - Wang2017 ER - TY - JOUR AU - Chen, Y. AU - Liu, Z. AU - Wang, H. AU - Tang, Z. AU - Liu, Y. AU - Liang, Z. PY - 2020 DA - 2020// TI - VPS33B negatively modulated by nicotine functions as a tumor suppressor in colorectal cancer JO - Int J Cancer VL - 146 ID - Chen2020 ER - TY - JOUR AU - Kim, S. M. AU - Hwang, K. A. AU - Choi, D. W. AU - Choi, K. C. PY - 2018 DA - 2018// TI - The cigarette smoke components induced the cell proliferation and epithelial to mesenchymal transition via production of reactive oxygen species in endometrial adenocarcinoma cells JO - Food Chem Toxicol VL - 121 ID - Kim2018 ER - TY - JOUR AU - Dasgupta, P. AU - Rizwani, W. AU - Pillai, S. AU - Kinkade, R. AU - Kovacs, M. AU - Rastogi, S. PY - 2009 DA - 2009// TI - Nicotine induces cell proliferation, invasion and epithelial-mesenchymal transition in a variety of human cancer cell lines JO - Int J Cancer VL - 124 ID - Dasgupta2009 ER - TY - JOUR AU - Panciera, T. AU - Azzolin, L. AU - Cordenonsi, M. AU - Piccolo, S. PY - 2017 DA - 2017// TI - Mechanobiology of YAP and TAZ in physiology and disease JO - Nat Rev Mol Cell Biol VL - 18 ID - Panciera2017 ER - TY - JOUR AU - Murakami, S. AU - Nemazanyy, I. AU - White, S. M. AU - Chen, H. AU - Nguyen, C. D. K. AU - Graham, G. T. PY - 2019 DA - 2019// TI - A yap-Myc-Sox2-p53 regulatory network dictates metabolic homeostasis and differentiation in Kras-driven pancreatic ductal adenocarcinomas JO - Dev Cell VL - 51 ID - Murakami2019 ER - TY - JOUR AU - Eibl, G. AU - Rozengurt, E. PY - 2019 DA - 2019// TI - KRAS, YAP, and obesity in pancreatic cancer: a signaling network with multiple loops JO - Semin Cancer Biol VL - 54 ID - Eibl2019 ER - TY - JOUR AU - Shen, Y. AU - Zhao, S. AU - Wang, S. AU - Pan, X. AU - Zhang, Y. AU - Xu, J. PY - 2019 DA - 2019// TI - S1P/S1PR3 axis promotes aerobic glycolysis by YAP/c-MYC/PGAM1 axis in osteosarcoma JO - EBioMedicine VL - 40 ID - Shen2019 ER - TY - JOUR AU - Yao, F. AU - Zhou, Z. AU - Kim, J. AU - Hang, Q. AU - Xiao, Z. AU - Ton, B. N. PY - 2018 DA - 2018// TI - SKP2- and OTUD1-regulated non-proteolytic ubiquitination of YAP promotes YAP nuclear localization and activity JO - Nat Commun VL - 9 ID - Yao2018 ER - TY - JOUR AU - Guo, H. AU - Liu, J. AU - Ben, Q. AU - Qu, Y. AU - Li, M. AU - Wang, Y. PY - 2016 DA - 2016// TI - The aspirin-induced long non-coding RNA OLA1P2 blocks phosphorylated STAT3 homodimer formation JO - Genome Biol VL - 17 ID - Guo2016 ER - TY - JOUR AU - Zhao, B. AU - Li, L. AU - Tumaneng, K. AU - Wang, C. Y. AU - Guan, K. L. PY - 2010 DA - 2010// TI - A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF (beta-TRCP) JO - Genes Dev VL - 24 ID - Zhao2010 ER - TY - JOUR AU - Wang, Y. AU - He, J. AU - Jiang, H. AU - Zhang, Q. AU - Yang, H. AU - Xu, X. PY - 2018 DA - 2018// TI - Nicotine enhances storeoperated calcium entry by upregulating HIF1alpha and SOCC components in nonsmall cell lung cancer cells JO - Oncol Rep VL - 40 ID - Wang2018 ER - TY - JOUR AU - Zhang, Q. AU - Tang, X. AU - Zhang, Z. F. AU - Velikina, R. AU - Shi, S. AU - Le, A. D. PY - 2007 DA - 2007// TI - Nicotine induces hypoxia-inducible factor-1alpha expression in human lung cancer cells via nicotinic acetylcholine receptor-mediated signaling pathways JO - Clin Cancer Res VL - 13 ID - Zhang2007 ER - TY - JOUR AU - Zhou, T. Y. AU - Zhuang, L. H. AU - Hu, Y. AU - Zhou, Y. L. AU - Lin, W. K. AU - Wang, D. D. PY - 2016 DA - 2016// TI - Inactivation of hypoxia-induced YAP by statins overcomes hypoxic resistance tosorafenib in hepatocellular carcinoma cells JO - Sci Rep VL - 6 ID - Zhou2016 ER - TY - JOUR AU - Zhang, X. AU - Li, Y. AU - Ma, Y. AU - Yang, L. AU - Wang, T. AU - Meng, X. PY - 2018 DA - 2018// TI - Yes-associated protein (YAP) binds to HIF-1alpha and sustains HIF-1alpha protein stability to promote hepatocellular carcinoma cell glycolysis under hypoxic stress JO - J Exp Clin Cancer Res VL - 37 ID - Zhang2018 ER - TY - STD TI - Tan Z, Xu J, Zhang B, Shi S, Yu X, Liang C. Hypoxia: a barricade to conquer the pancreatic cancer. Cell Mol Life Sci. 2020;77:3077–83. ID - ref50 ER -