Skip to main content
Fig. 6 | Journal of Experimental & Clinical Cancer Research

Fig. 6

From: Hsa_circ_0001944 promotes the growth and metastasis in bladder cancer cells by acting as a competitive endogenous RNA for miR-548

Fig. 6

Downregulation miR-548 or overexpression PROK2 restored the proliferation and invasiveness of BC cells after has_circ_0001944 was silenced. a-c Colony formation assays show the proliferation of both T24 and UMUC3 cells after transfection with si-hsa_circ_0001944, miR-548 inhibitor, or PROK2 overexpression vector, either singly or in combination. Data are means ± SD. ***P < 0.001 vs. NC. ###P < 0.001 vs. si-circRNA. d-f Edu assay shows the proliferation of both T24 and UMUC3 cells after transfection with si-has_circ_0001944, miR-548 inhibitor, or PROK2 overexpression vector, either singly or in combination. Data are means ± SD. ***P < 0.001 vs. NC. ###P < 0.001 vs. si-circRNA. g-i Transwell migration assays of both T24 and UMUC3 cells. Data are means ± SD. ***P < 0.001 vs. NC. ###P < 0.001 vs. si-circRNA

Back to article page