Fig. 7

PROK2 overexpression rescued the proliferation and invasiveness of BC cells after miR-548 upregulation. a-c Colony formation assays show the proliferation of both T24 and UMUC3 cells after transfection with miR-548 mimic or PROK2 overexpression vector, either singly or in combination. Data are means ± SD. ***P < 0.001 vs. NC. ^###P < 0.001 vs. si-circRNA. d-f Edu assays show the proliferation of both T24 and UMUC3 cells after transfection with si-hsa_circ_0001944, hsa_circ_0001944 inhibitor, or PROK2 overexpression vector, either singly or in combination. Data are means ± SD. ***P < 0.001 vs. NC. ^###P < 0.001 vs. si-circRNA. (G-I) Transwell migration assays of both T24 and UMUC3 cells. Data are means ± SD. ***P < 0.001 vs. NC. ^###P < 0.001 vs. si-circRNA