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Fig. 7 | Journal of Experimental & Clinical Cancer Research

Fig. 7

From: Lysosomal dysfunction and autophagy blockade contribute to autophagy-related cancer suppressing peptide-induced cytotoxic death of cervical cancer cells through the AMPK/mTOR pathway

Fig. 7

ARCSP-induced autophagy has antitumor effects in vivo. a-b HeLa xenograft tumors in the control group and ARCSP-treated group were measured once a day for 25 days. a Body weight change. b Tumor volume change. c The final tumor weights were measured. d An image of a representative tumor is shown. e The levels of LC3B-II/I and Atg7 were detected by Western blotting. f Immunohistochemical staining with LC3B, Bax, Ki67 and PCNA antibodies in tumor tissue (shown as brown staining). Scale bar = 50 μm. The data are expressed as the mean ± SD; *P < 0.05, **P < 0.01, ***P < 0.001. ns, not significant

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