Fig. 7

CRT silencing inhibited subcutaneous tumor size and distant liver metastasis in vivo. a The representative images and statistical data of tumor volumes between scramble and sg2-CRT groups in nude mice. b The representative HE and IHC images of CRT and IRE1α expression in subcutaneous tumor between scramble and sg2-CRT groups. c The representative images and statistical data of the number of liver metastases between scramble and sg2-CRT groups in nude mice. d The representative HE and IHC images of CRT and IRE1α expression in distant liver metastasis between scramble and sg2-CRT groups. Data are shown as mean ± SD. *P < 0.05 versus control. Data are shown as mean ± SD. *P < 0.05 versus control.1: Scramle; 2: sg2-CRT