Fig. 4

Effects of TRPV1 genetic manipulation on GC cell migration, invasion and metastasis. GC cell migration presented as original images and presented as summary data in TRPV1-overexpressed BGC823 cells (a) and TRPV1-knockeddown MKN45 cells (b) (*P < 0.05, **P < 0.01 vs. NC, n = 3). GC cell invasion presented as original images in and presented as summary data in TRPV1-overexpressed BGC823 cells (c) and TRPV1-knockeddown MKN45 cells (d) (*P < 0.05, **P < 0.01 vs. NC, n = 3). e Images of nude mice peritoneally injected with NC cells (left) and TRPV1-overexpressed BGC823 cells (right). f Summary data of tumor numbers from each groups of abdominal transplantation mouse model (**P < 0.01 vs. NC, n = 7 mice)