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Fig. 1 | Journal of Experimental & Clinical Cancer Research

Fig. 1

From: Tubulin Tyrosine Ligase Like 4 (TTLL4) overexpression in breast cancer cells is associated with brain metastasis and alters exosome biogenesis

Fig. 1

TTLL4 mRNA levels in breast cancer tumour tissue. a-e Correlation of TTLL4 mRNA levels with clinical and histological parameters. Significant associations of high TTLL4 levels with positive nodal status (a), higher grading (b), HER2+ and TNBC subtypes (c) and brain metastasis formation (d) are shown. Additionally, Kaplan-Meier analysis shows a correlation between high TTLL4 mRNA levels with shorter recurrence-free (e) and overall survival (f). P-values after log-rank tests comparing two groups (TTLL4 levels < 75% vs. TTLL4 levels > 75%) are shown

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