Fig. 1

m6A modification was activated in colon cancer. a. Heatmap of all m6A associated enzymes in colon cancer analyzed based on TCGA database. b. Co-expression of m6A associated enzymes analyzed and visualized by R software based on Pearson Correlation Coefficient analysis. c. The mRNA expression of m6A associated enzymes in both colon cancer and normal bowel tissues analyzed (red asterisk: overexpressed in tumor; blue asterisk: downregulated in tumor). d. m6A level of total RNA in colon cancer and normal bowel tissues (n = 25, ns: no significance). e. Copy number variation of coding genes of m6A associated enzymes. f. Somatic mutations of coding genes of m6A associated enzymes. (ns: no significance, *P<0.05, **p < 0.01, ***P<0.001)