Fig. 3

The combination effects of CUDC-907 and olaparib. a CellTiter-Glo Luminescent assays demonstrating the effects of 10 nM CUDC-907 and 10 μM olaparib in seven SCLC cell lines. b Apoptosis assessment of SCLC cells following 10 nM CUDC-907 and 10 μM olaparib as single-agents or in combination for 48 h. c Western blot analysis of cleavage of PARP and caspase 3, and γH2AX in SCLC cells upon treatment with 10 nM CUDC-907 or 10 μM olaparib alone or in combination for 24 h. CC3, cleaved caspase 3