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Fig. 1 | Journal of Experimental & Clinical Cancer Research

Fig. 1

From: Activation of the KDM5A/miRNA-495/YTHDF2/m6A-MOB3B axis facilitates prostate cancer progression

Fig. 1

KDM5A is highly expressed in the PCa tissues and cells, and it predicts a poor prognosis. a, KDM5A mRNA expression in PCa and adjacent normal tissues of patients detected by RT-qPCR. N = 78 for PCa patients. b, Western blot analysis and immunohistochemistry of KDM5A protein in PCa and adjacent normal tissues of patients. N = 78 for PCa patients. c, Corelation of KDM5A expression with DFS and OS analyzed using the Kaplan-Meier method. d, KDM5A mRNA expression in RWPE-1, LNCaP, C42, DU145 and PC3 cells detected by RT-qPCR. e and f, Western blot analysis and quantification of KDM5A protein in RWPE-1, LNCaP, C42, DU145 and PC3 cells. * p < 0.05 vs. RWPE-1 cells. Data in panel A and B were analyzed by paired t-test and those in panel C-E were analyzed by one-way ANOVA with Tukey’s post hoc test

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