Fig. 3

Evodiamine increases cell apoptosis in H1650 and H1975 in a MUC1-C-dependent manner. a-b The Western blot assays results show that MUC1-C was successfully knocked down in H1650 and H1975cells. c-f The percent of apoptosis cells is analyzed by using flow cytometry. g-h The MTT results also demonstrated that evodiamine increases cell apoptosis and inhibits growth in H1650 and H1975 via the MUC1-C dependent. The results were presented in three independent experiments with the mean ± S.D. (n = 3, *P < 0.05; **P < 0.01; ***P < 0.001)