Fig. 2

Increased expression of circ_001287 in RCC tissues and cells. a, Expression of circ_001287 in RCC tissues and adjacent normal tissues detected using RT-qPCR (n = 77). b, Scatter plot of circ_001287 expression in RCC tissues and adjacent normal tissues. c, Expression of circ_001287 in normal renal tubular epithelial cell line and RCC cell lines using RT-qPCR. ^*p < 0.05 vs. normal adjacent tissues or HK-2 cell line. The data were measurement data and presented as mean ± standard deviation. Data between two groups were analyzed using paired t-test and data among groups were compared with one-way ANOVA, followed by Tukey’s post hoc test. The cell experiment was repeated 3 times. circRNA, circular RNA; RT-qPCR, reverse transcription quantitative polymerase chain reaction