Extracellular vesicular Wnt7b mediates HPV E6-induced cervical cancer angiogenesis by activating the β-catenin signaling pathway

Table 1 The correlations between the expression of serum EV-Wnt7b and clinicopathological factors of SCC patients

Variable	Low expression of serum EV-Wnt7b (n = 51)	High expression of serum EV-Wnt7b (n = 50)	P
Age, y (mean ± SD)			0.203
< =45	17	11
> 45	34	39
Stage			0.617
I	37	34
II	14	16
Tumor size			0.115
< =4 cm	39	31
> 4 cm	12	19
Lymphovascular invasion			< 0.001
Negative	33	10
Positive	18	40
Stromal invasion depth			0.028
< 1/2	24	13
> =1/2	27	37
Lymph node metastasis			< 0.001
Negative	45	25
Positive	6	25
Parametrial invasion			0.269
Negative	49	45
Positive	2	5
Margin			0.984
Negative	49	48
Positive	2	2

ISSN: 1756-9966