Fig. 1

Downregulation of miR-7e-5p in the transformation of FL to DLBCL. a The expression of six miRNAs was compared in low-grade FL, high-grade FL and DLBCL tissue samples by real-time PCR. The median miRNA expression was calculated and is presented in the heatmap. Pink represents high expression, and blue represents low expression. b Differential expression of miR-7e-5p in low-grade FL, high-grade FL, DLBCL tissue samples by real-time PCR. Statistical test: Mann-Whitney U test. c Decreased expression of miR-7e-5p in five paired tissues with FL-tFL transformation. Statistical test: t-test. d The level of miR-7e-5p was decreased in FL cell lines compared to DLBCL cell lines. Statistical test: t-test