Fig. 6From: MiR-7e-5p downregulation promotes transformation of low-grade follicular lymphoma to aggressive lymphoma by modulating an immunosuppressive stroma through the upregulation of FasL in M1 macrophagesFasL increases the apoptosis of M1 cells by binding Fas in patients. a Representative example of HE and IHC stains for Fas and FasL expression in tumor cells in low-grade FL and high-grade FL patient tissues. Original magnification × 400, top right corner × 800. HE: hemotoxylin and eosin staining. Scale bars: 20 μm. b IHC score for Fas and FasL expression levels in tumor cells from eight low-grade FL samples and eight high-grade FL samples. Statistical test: t-test. c Representative example of HE and IHC stains for FasL, CD68, CD163, Caspase3 and Caspase 8 in macrophage cells in low-grade FL and high-grade FL patient tissues. Original magnification × 400, top right corner × 800. Scale bars: 20 μm. d IHC scores for FasL, CD68, CD163, Caspase3 and Caspase 8 expression levels in macrophage cells in eight low-grade FL and eight high-grade FL samples. Statistical test: t-testBack to article page