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Fig. 7 | Journal of Experimental & Clinical Cancer Research

Fig. 7

From: MiR-7e-5p downregulation promotes transformation of low-grade follicular lymphoma to aggressive lymphoma by modulating an immunosuppressive stroma through the upregulation of FasL in M1 macrophages

Fig. 7

Downregulation of miR-7e-5p induces FL transformation via the activation of apoptotic signaling in macrophages. Scheme illustrating the mechanism the regulatory function of miR-7e-5p in recipient M1 macrophages. Downregulation of lymphoma-derived miR-7e-5p activates Fas-FasL interaction and downstream Caspase signaling in macrophages

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Journal of Experimental & Clinical Cancer Research

ISSN: 1756-9966

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