Fig. 4

Overexpression of UPK1A-AS1 boosts tumor growth in HCC. a-c. Overexpression of UPK1A-AS1 in MHCC-97H cells promoted tumor growth in vivo. Tumor burden and tumor weight in cells with UPK1A-AS1 overexpression were visibly higher than those of control cells (^*P < 0.05, ^**P < 0.01). d. Expression of UPK1A-AS1 in the subcutaneous tumor was determined by qRT-PCR (^**P < 0.01). e. Sections of xenograft tumors stained with hematoxylin and eosin (h&e); Ki-67 staining was performed for further determination of the effect of UPK1A-AS1 on cell proliferation