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Fig. 2 | Journal of Experimental & Clinical Cancer Research

Fig. 2

From: Loss of PLK2 induces acquired resistance to temozolomide in GBM via activation of notch signaling

Fig. 2

Decreased PLK2 expression is closely associated with poor outcomes in glioma patients. a, Gene expression analysis using TCGA GBM database (*P < .05, with student’s t-test). b, Gene expression analysis with Rembrandt database in different types of glioma versus non-tumor (*P < .05, **P < .01, ***P < .001, with one-way ANOVA followed by Dunnett’s posttest). c, Gene expression analysis with TCGA GBM dataset in different subtypes of GBM versus non-tumor (***P < .001, with one-way ANOVA followed by Dunnett’s posttest). d. Kaplan-Meier analysis for PLK2 expression using GBM patient samples (P < .0001, with log-rank test). e, Kaplan-Meier analysis for PLK2 expression in Rembrandt dataset by dividing glioma samples into 3 groups including PLK2high, PLK2mid, PLK2low (with log-rank test within each comparison)

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