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Fig. 3 | Journal of Experimental & Clinical Cancer Research

Fig. 3

From: MiRNA-340-5p mediates the functional and infiltrative promotion of tumor-infiltrating CD8+ T lymphocytes in human diffuse large B cell lymphoma

Fig. 3

CD8+ T-cell immune function is facilitated by miR-340-5p. a Representative ISH images of the association between miR-340-5p expression and CD8+ T-TILs in DLBCL patients. Magnification of the microscope: left column, 40×; right column, 200×. b Schema for coculturing CD8+ T cells and DLBCL cells. c-d The representative proportion (c) and cumulative data (d) of CD69hi cells in CD8+ T cells. e-f Cytokine production assays (IFN-γ, TNF-α, and IL-2) were performed for CD8+ T cells directly (e) or indirectly (f) cocultured with DLBCL cell lines transfected with m-NC or miR-340-5p. Asterisk (*) indicates a significant difference. *, P < 0.05

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