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Fig. 1 | Journal of Experimental & Clinical Cancer Research

Fig. 1

From: The molecular and gene/miRNA expression profiles of radioiodine resistant papillary thyroid cancer

Fig. 1

Flowchart of patients and tissues selection. Starting from a database of 1339 patients, subsequent strict selections were done in order to identify patients for whom a radioiodine (RAI) avidity or refractoriness could be definitely determined. Seventy primary papillary thyroid cancer (PTC) tissues were included, divided according to the RAI class (RAI+/D+: initial RAI uptake but disease persistence, RAI−/D+: without RAI uptake and disease persistence, and RAI+/D-: RAI uptake and disease remission), and submitted to the analyses of multiple PTC-related gene mutations and fusions by a PTC-Mass Array platform. The subset of tissues submitted to gene/miRNA arrays are reported. They included primary PTCs, synchronous lymph node metastasis (LNM), RAI refractory LNM (collected after RAI treatment), and non-neoplastic thyroid (NT)

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