Fig. 7

The effect of circMCTP2 on autophagy is reversed by the downregulation of MTMR3. a-d Confocal microscopy analysis showing the accumulation of GFP/mRFP-LC3 dots. e and f Western blotting showing the expression levels of Beclin1, p62, and LC3-II proteins. g and h TEM analysis showing the autophagic microstructure in CDDP-resistant GC cells. CDDP treatment: 12 μM for 48 h in BGC823CDDP cells and 6 μM for 48 h in SGC7901CDDP cells. (*p < 0.05, **p < 0.01. Data are expressed as the means ± SDs)