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Fig. 2 | Journal of Experimental & Clinical Cancer Research

Fig. 2

From: Glycometabolic rearrangements--aerobic glycolysis in pancreatic cancer: causes, characteristics and clinical applications

Fig. 2

Metabolic reaction in PDAC cells, especially aerobic glycolysis in pancreatic cancer cells. Glycolysis is the main form of energy production in pancreatic cancer, even under normoxia. However, there are also some cancer cells that produce energy through oxidative phosphorylation. GLUT: glucose transporter; G-6-P: glucose-6-phosphate; F-6-P: fructose-6-phosphate; F-1,6-BP: fructose-1,6-biphosphate. 1: Hexokinase; 2: phosphohexose isomerase; 3: phosphofructokinase; 4: aldolase; 5: triose phosphate isomerase; 6: glyceraldehyde 3-phosphate dehydrogenase; 7: phosphoglycerate kinase; 8: phosphoglycerate mutase; 9: enolase; 10: pyruvate kinase 11: lactate dehydrogenase

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