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Table 4 KEGG pathways involved in GOLPH3L-silenced breast cancer cells

From: The miR-1185-2-3p—GOLPH3L pathway promotes glucose metabolism in breast cancer by stabilizing p53-induced SERPINE1

Database ID P-Value Corrected P-Value Genes
KEGG PATHWAY hsa04933 5.42713E-07 7.32662E-05 CCL2;PIK3CB;SERPINE1;KRAS;TGFB2
KEGG PATHWAY hsa05142 2.07617E-05 0.001401414 CCL2;PIK3CB;TGFB2;SERPINE1
KEGG PATHWAY hsa05210 0.000126423 0.003878901 PIK3CB;TGFB2;KRAS
KEGG PATHWAY hsa05212 0.000151007 0.003878901 PIK3CB;TGFB2;KRAS
KEGG PATHWAY hsa05211 0.000157602 0.003878901 PIK3CB;TGFB2;KRAS
KEGG PATHWAY hsa04062 0.00018996 0.003878901 CCL2;PIK3CB;KRAS;CCR2
KEGG PATHWAY hsa05220 0.000201128 0.003878901 PIK3CB;TGFB2;KRAS
KEGG PATHWAY hsa04211 0.000412618 0.006962933 PIK3CB;KRAS;ADIPOQ
KEGG PATHWAY hsa05160 0.001101508 0.01518735 PIK3CB;KRAS;CLDN1
KEGG PATHWAY hsa04068 0.001124989 0.01518735 PIK3CB;TGFB2;KRAS
KEGG PATHWAY hsa04530 0.001247139 0.015305797 VAPA;KRAS;CLDN1
KEGG PATHWAY hsa05161 0.001431726 0.016106915 PIK3CB;TGFB2;KRAS
KEGG PATHWAY hsa04960 0.001705229 0.017708152 PIK3CB;KRAS
KEGG PATHWAY hsa04360 0.002413822 0.022159731 EFNB2;PIK3CB;KRAS
KEGG PATHWAY hsa04930 0.002525744 0.022159731 PIK3CB;ADIPOQ
KEGG PATHWAY hsa05144 0.002626339 0.022159731 CCL2;TGFB2
KEGG PATHWAY hsa05213 0.00293929 0.023341421 PIK3CB;KRAS
KEGG PATHWAY hsa05223 0.003382408 0.024852551 PIK3CB;KRAS
KEGG PATHWAY hsa05221 0.003497766 0.024852551 PIK3CB;KRAS
KEGG PATHWAY hsa05205 0.003682986 0.024860155 PIK3CB;TGFB2;KRAS
KEGG PATHWAY hsa04370 0.003977354 0.025568702 PIK3CB;KRAS
KEGG PATHWAY hsa04213 0.004355952 0.026010475 PIK3CB;KRAS
KEGG PATHWAY hsa05214 0.004485724 0.026010475 PIK3CB;KRAS
KEGG PATHWAY hsa05230 0.004750595 0.026010475 PIK3CB;SERPINE1
KEGG PATHWAY hsa04664 0.004885683 0.026010475 PIK3CB;KRAS
KEGG PATHWAY hsa05218 0.005301493 0.026010475 PIK3CB;KRAS
KEGG PATHWAY hsa04917 0.005443594 0.026010475 PIK3CB;KRAS
KEGG PATHWAY hsa03320 0.005443594 0.026010475 OLR1;ADIPOQ
KEGG PATHWAY hsa04662 0.005587435 0.026010475 PIK3CB;KRAS
KEGG PATHWAY hsa01521 0.006800173 0.030390563 PIK3CB;KRAS
KEGG PATHWAY hsa05166 0.006978574 0.030390563 PIK3CB;TGFB2;KRAS
KEGG PATHWAY hsa04060 0.007424504 0.031322125 CCL2;TGFB2;CCR2
KEGG PATHWAY hsa04012 0.007950284 0.032246156 PIK3CB;KRAS
KEGG PATHWAY hsa05215 0.008121254 0.032246156 PIK3CB;KRAS
KEGG PATHWAY hsa05323 0.008468143 0.032662838 CCL2;TGFB2
KEGG PATHWAY hsa01522 0.009548044 0.034763406 PIK3CB;KRAS
KEGG PATHWAY hsa04914 0.009733696 0.034763406 PIK3CB;KRAS
KEGG PATHWAY hsa04915 0.009920954 0.034763406 PIK3CB;KRAS
KEGG PATHWAY hsa05146 0.010109813 0.034763406 PIK3CB;TGFB2
KEGG PATHWAY hsa05231 0.010300268 0.034763406 PIK3CB;KRAS
KEGG PATHWAY hsa04066 0.010685948 0.035185438 PIK3CB;SERPINE1
KEGG PATHWAY hsa04660 0.011077952 0.035607703 PIK3CB;KRAS
KEGG PATHWAY hsa04668 0.012085376 0.037712623 CCL2;PIK3CB
KEGG PATHWAY hsa04725 0.012291521 0.037712623 PIK3CB;KRAS
KEGG PATHWAY hsa04919 0.013777442 0.039775364 PIK3CB;KRAS
KEGG PATHWAY hsa04670 0.013777442 0.039775364 PIK3CB;CLDN1
KEGG PATHWAY hsa05145 0.013995787 0.039775364 PIK3CB;TGFB2
KEGG PATHWAY hsa04722 0.014215636 0.039775364 PIK3CB;KRAS
KEGG PATHWAY hsa04071 0.014436984 0.039775364 PIK3CB;KRAS
KEGG PATHWAY hsa04152 0.015337266 0.041410618 PIK3CB;ADIPOQ
KEGG PATHWAY hsa04380 0.016969364 0.044918905 PIK3CB;TGFB2
KEGG PATHWAY hsa04650 0.01769056 0.045927416 PIK3CB;KRAS
KEGG PATHWAY hsa04910 0.018672129 0.047302645 PIK3CB;KRAS
KEGG PATHWAY hsa04210 0.018921058 0.047302645 PIK3CB;KRAS
KEGG PATHWAY hsa04550 0.019423126 0.047674946 PIK3CB;KRAS
KEGG PATHWAY hsa04072 0.019930779 0.048047414 PIK3CB;KRAS
KEGG PATHWAY hsa05200 0.021609077 0.05050568 PIK3CB;TGFB2;KRAS
KEGG PATHWAY hsa04932 0.021751022 0.05050568 PIK3CB;ADIPOQ
KEGG PATHWAY hsa04390 0.022551551 0.05050568 TGFB2;SERPINE1
KEGG PATHWAY hsa04150 0.022551551 0.05050568 PIK3CB;KRAS
KEGG PATHWAY hsa04145 0.022821085 0.05050568 VAMP3;OLR1
KEGG PATHWAY hsa04921 0.023637696 0.051469176 PIK3CB;KRAS
KEGG PATHWAY hsa05164 0.028783631 0.06167921 CCL2;PIK3CB
KEGG PATHWAY hsa05168 0.031818708 0.067117587 CCL2;TAF9B
KEGG PATHWAY hsa04977 0.036402182 0.075604532 LMBRD1
KEGG PATHWAY hsa05169 0.037582935 0.076394178 POLR3G;PIK3CB
KEGG PATHWAY hsa05203 0.037914147 0.076394178 PIK3CB;KRAS
KEGG PATHWAY hsa04015 0.039924992 0.079262851 PIK3CB;KRAS
KEGG PATHWAY hsa04810 0.041287714 0.08078031 PIK3CB;KRAS
KEGG PATHWAY hsa04320 0.042104357 0.081201261 KRAS
KEGG PATHWAY hsa05216 0.04352471 0.082758252 KRAS
KEGG PATHWAY hsa04014 0.045835719 0.085941973 PIK3CB;KRAS
KEGG PATHWAY hsa00640 0.047773358 0.0871541 ECHDC1
KEGG PATHWAY hsa03020 0.047773358 0.0871541 POLR3G
  1. Legends: KEGG pathways of different metabolites that were altered significantly after GOLPH3L silencing, p-values< 0.05
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Journal of Experimental & Clinical Cancer Research

ISSN: 1756-9966

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