Fig. 5

Radiation treatment alters relative histone peptide modification states in DIPG, in vitro. a Unsupervised hierarchical clustering of pediatric glioma cell line histone tail modification profiles reveals clustering by cell line and treatment condition. b-d Relative abundance of H2AK5ac, H4K16ac and H3K9me3 peptides are distinct after radiation treatment. * p < 0.05 compared to Baseline; # p < 0.05 compared to 24 h post-RT treatment (Tukey HSD, Post Hoc Tests, one way ANOVA)