Table 2 Comparison of DIPG Tumor tissue and cell line epiproteomic profiles. Differential fold change (FC) in abundance (> 2 or < 0.5) between DIPG tumor tissue and cell lines was detected only in the six H3.1/H3.3K27 peptide modification states listed
Histone code | Mean | Fold_Change | p value | |
|---|---|---|---|---|
Tissue | Cells | Tissue/Cells | Â | |
H3.3K36ac | 2.4 | 15.8 | 0.2 | < 0.01 |
H3K79me2 | 18.0 | 8.3 | 2.2 | < 0.05 |
H3.3K36me1 | 12.7 | 5.3 | 2.4 | < 0.05 |
H3K9ac | 5.6 | 2.0 | 2.8 | < 0.01 |
H4K20me3 | 8.5 | 2.2 | 3.9 | < 0.01 |
H1.4K25me1 | 29.7 | 5.1 | 5.8 | < 0.01 |