Table 1 Relation of WNT4, CA199, CEA expression with clinicopathological parameters of patients with CRC
Parameters | WNT4 (pg/mL) | P value | CA199 (U/mL) | P value | CEA (ng/mL) | P value | |||
|---|---|---|---|---|---|---|---|---|---|
Cases | Mean ± SEM | Cases | Mean ± SEM | Cases | Mean ± SEM | ||||
Age(y) | |||||||||
≤ 65 | 23 | 77.31 ± 10.04 | 0.9583 | 22 | 31.51 ± 10.27 | 0.3766 | 22 | 4.304 ± 1.315 | 0.7307 |
> 65 | 17 | 78.07 ± 9.623 | 16 | 19.78 ± 5.963 | 16 | 3.671 ± 1.143 | |||
Sex | |||||||||
Male | 20 | 88.46 ± 11.14 | 0.1129 | 19 | 28.36 ± 9.941 | 0.7862 | 19 | 4.445 ± 1.394 | 0.6533 |
Female | 20 | 66.81 ± 7.998 | 19 | 24.79 ± 8.484 | 19 | 3.629 ± 1.141 | |||
TNM T | |||||||||
I ∼ II | 13 | 55.94 ± 8.395 | 0.0293 | 13 | 26.84 ± 12.39 | 0.9768 | 12 | 1.135 ± 0.237 | 0.0247 |
III ∼ IV | 27 | 88.08 ± 8.941 | 25 | 26.44 ± 7.594 | 26 | 5.377 ± 1.216 | |||
TNM N | |||||||||
0 | 26 | 73.99 ± 9.211 | 0.4849 | 26 | 28.20 ± 8.763 | 0.7158 | 25 | 2.732 ± 0.769 | 0.0403 |
1–2 | 14 | 84.39 ± 10.49 | 12 | 23.05 ± 7.982 | 13 | 6.548 ± 2.021 | |||
TNM M | |||||||||
0 | 34 | 71.73 ± 6.868 | 0.0428 | 32 | 21.28 ± 5.175 | 0.0570 | 32 | 3.562 ± 0.76 | 0.2221 |
1 | 6 | 111.1 ± 22.62 | 6 | 54.80 ± 29.61 | 6 | 6.575 ± 4.071 | |||
TNM stage | |||||||||
Early(I/ II) | 24 | 66.35 ± 8.097 | 0.0464 | 24 | 22.71 ± 6.797 | 0.4407 | 23 | 2.710 ± 0.836 | 0.0642 |
Advanced (III/IV) | 16 | 94.57 ± 11.61 | 14 | 33.20 ± 13.27 | 15 | 6.072 ± 1.772 | |||
Grade | |||||||||
WD | 8 | 62.62 ± 14.33 | 0.5367 | 8 | 37.70 ± 19.55 | 0.6844 | 8 | 1.52 ± 0.41 | 0.3173 |
MD | 28 | 82.48 ± 8.83 | 27 | 23.70 ± 7.14 | 26 | 4.89 ± 1.24 | |||
PD | 4 | 73.76 ± 16.26 | 3 | 22.84 ± 3.32 | 4 | 3.50 ± 1.59 | |||
Tumor size | |||||||||
⩽3 cm | 18 | 59.38 ± 8.190 | 0.0087 | 17 | 25.53 ± 9.579 | 0.8158 | 17 | 3.853 ± 1.725 | 0.7530 |
> 3 cm | 20 | 96.60 ± 10.38 | 19 | 28.77 ± 9.850 | 19 | ||||