Fig. 7

Effect of JVG045 on FGFR1 and Src in HPAF-II mouse xenografts. a Representative western blot of two groups of tumours either vehicle treated (ctrl) or treated with JVG045 (30 mg/kg) and probed for pSrc (Y416) or pFGFR1(Y653/654). GAPDH was used as loading control. Averaged quantification of (b) pSrc(Y416) and (c) pFGFR1(Y653/654) western blot signals, normalised to their loading control in vehicle treated tumour xenografts (control) or tumour xenografts treated with JVG045 (30 mg/kg)