Fig. 2
From: Dexosomes as a cell-free vaccine for cancer immunotherapy
Dexosome function. a Direct presentation of antigens by dexosomes to T cells (Antigens are not captured or processed by DC in this pathway). b Indirect presentation of antigens by dexosomes to T cells. Here, antigens are first captured and processed by DCs through the endocytic pathway and are subsequently cross-presented on DC surface to T cells. c Indirect antigen presentation to DCs through cross-dressing of DCs by dexosomes. d Indirect antigen presentation by dexosomes to DCs via tumor cells. Here, antigens, i.e. TAAs, are captured by tumor cells and then cross-presented to T cells