Skip to main content
Fig. 1 | Journal of Experimental & Clinical Cancer Research

Fig. 1

From: Alcoholic fatty liver disease inhibited the co-expression of Fmo5 and PPARα to activate the NF-κB signaling pathway, thereby reducing liver injury via inducing gut microbiota disturbance

Fig. 1

Bacterial community analysis and comparison. a Number of Tags/or 16S OTUs amongst mice with AFLD. b Core bacterial operational taxonomic units (OTUs) in mice from different groups. The core community was determined based on OTUs detected in every sample. The OTUs were assigned at a 97% sequences similarity threshold, and a Venn diagram was used to summarize the number of common OTUs between the two groups. The composition and abundance distributions of each group at the phylum (c) and family (f) levels were shown using QIIME software. At the phylum (d and e) and family (g) levels, pairwise comparisons, conducted to determine the sequence amounts between two groups, were presented as pair-wise comparisons using Metastats analysis. ** represents P < 0.01 compared with the CON group. A heat map of genera at the phylum (h) and family (i) levels were shown. Red represents upregulation and green represents downregulation. (j) The alpha diversity (observed species, Shannon, Simpson, ACE, Chao1, and Good’s coverage) of intestinal flora between CON group and AFLD group was shown. Cluster analysis result for both CON group and AFLD group according to NMDS (k) and Principal coordinate analysis (PCoA) (l). PCoA was performed using Bray-Curtis

Back to article page