Cancer type | Clinicopathological features | References |
---|---|---|
thyroid carcinoma | Low MIR22HG expression was related to tumor size (P = 0.015), TNM stage (P = 0.022) and poor overall survival (P = 0.030). | [21] |
Low MIR22HG expression was significantly related to the lymph node metastasis status (P < 0.01), the residual tumor status (P < 0.05), N stage (P < 0.05), tumor grade (P < 0.001) and T stage (P < 0.001) while high MIR22HG expression was significantly correlated with the disease recurrence rate (P < 0.01), overall survival time (P = 0.0665) and disease-free survival time (P < 0.05) in TC by analyzing TCGA, the GSE29265, GSE33630, and GSE55091 public datasets. | [22] | |
hepatocellular carcinoma | Low MIR22HG expression was associated with short overall survival (P = 0.045) and poor disease-free survival (P = 0.036). | [23] |
Patients with high MIR22HG expression exhibited better overall survival (145-patient cohort: P = 0.001; TCGA cohort: P = 0.015) and disease-free survival (145-patient cohort: P = 0.042; TCGA cohort: P = 0.003) than those with low MIR22HG expression. | [24] | |
cholangiocarcinoma | Low MIR22HG expression was positively correlated with advanced clinical stage (TNM) (P = 0.039), large tumor size (P = 0.002), lymph node metastasis (P = 0.0001), and poor overall survival (P = 0.020). | [26] |
colorectal cancer | Low MIR22HG expression was significantly associated with poor overall survival (P = 0.0008) and disease-free survival (P = 0.0009). | [27] |
gastric cancer | Low MIR22HG expression indicated a low 5-year overall survival rate (P < 0.05). | [28] |
non-small cell lung cancer | Low MIR22HG expression was correlated with poor patient survival (P = 0.003) in an independent UM cohort including 101 LUAD tissues and 27 normal lung tissues. | [30] |
glioblastoma | High MIR22HG expression was associated with patient age (P < 0.001), Karnofsky Performance Status score (P < 0.001), advanced tumor grade and poor overall survival (P < 0.05). | [31] |