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Fig. 6 | Journal of Experimental & Clinical Cancer Research

Fig. 6

From: Choline kinase alpha impairment overcomes TRAIL resistance in ovarian cancer cells

Fig. 6

CHKA silencing promoted TRAIL-R2 membrane relocation. a. Representative flow cytometry analysis indicating TRAIL-R2 membrane expression following primary antibody incubation at 37 °C in siCHKA and control OC cell lines. Fluorescence index are reported. b. Representative Western blotting analysis of TX-soluble and TX-insoluble fractions for TRAIL-R2 expression after CHKA silencing (left panel) and following recovery of ChoKα expression (middle panel): Cav-1 and Flot-1 were used as markers of TX-insoluble fractions. Right panel: densitometric analysis of relative TRAIL-R2 relocation in TX-insoluble fraction following silencing (white bars) and recovery of Chokα (black bars)

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