Table 1 Immunohistochemical expression of Estrogen Receptor (ER), Progesterone Receptor (PgR) and HER2 in pre- and post-treatment bioptical tissue samples from 4 HER2+, pertuzumab pretreated, advanced breast cancer patients
Pre-treatment | Post-treatment | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
ER | PgR | HER2 score | HER2% | FISH | ER | PgR | HER2 score | HER2% | FISH | |
Patient 1 | 90% | 90% | 2+ | 70% | amplified | 90% | 90% | 0 | 0% | – |
Patient 2 | 90% | 40% | 2+ | 30% | amplified | 90% | 60% | 1+ | 30% | – |
Patient 3 | 46% | 0% | 2+ | 100% | amplified | 75% | 18% | 1+ | 15% | amplified |
Patient 4 | 88% | 42% | 3+ | 100% | – | 99% | 1% | 1+ | 60% | amplified |