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Table 3 LncRNAs that regulate AS in cancer

From: Noncoding RNAs regulate alternative splicing in Cancer

LncRNA

Function

Cancer

Reference

Saf

Interaction with Fas pre-mRNA through the cis-NAT form

Leukemia, cervical cancer

[44]

EGOT

Interaction with ITPR1 pre-mRNA through the cis-NAT form

Breast cancer

[46]

Zeb2

Interaction with Zeb2 pre-mRNA through the cis-NAT form

Breast cancer

[47]

BC200

Interaction with Bcl-x pre-mRNA through the trans-NAT form

Breast cancer

[50]

CCAT2

Interaction with GLS pre-mRNA through the trans-NAT form

Colorectal cancer

[52]

UCA1

Sponging miR-184-mediated AS

Oral squamous cell carcinoma

[77]

CCAT1

Sponging miR-490-mediated AS

Gastric cancer

[64]

MALAT1

Promoting SRPK1-catalyzed SRSF1 phosphorylation

Colorectal cancer

[80]

LINC01133

Decoying the SF SRSF6 away from the targeted pre-mRNA

Colorectal cancer

[92]

PCGEM1

Decoying the SF HnRNPA1 away from the targeted pre-mRNA

Prostate cancer

[87]

TPM1-AS

Decoying the SF RBM4 away from the targeted pre-mRNA

Esophageal cancer

[88]

FAS-AS1

Decoying the SF RBM5 away from the targeted pre-mRNA

B-cell lymphomas

[93]

PNCTR, PANDAR, LUCAT1

Decoying the SF PTBP1 away from the targeted pre-mRNA

Cervical cancer osteosarcoma, colorectal cancer

[89], [94], [95]

MALAT1

Decoying the SF SFPQ away from the targeted pre-mRNA

Colorectal cancer

[96]

Gomafu

Decoying the SF SF1 and Celf3 away from the targeted pre-mRNA

Neuroblastoma

[97]

Spry1

Decoying the SF U2AF65 away from the targeted pre-mRNA

Breast cancer

[98]

LASTR

Decoying the SF SART3 away from the targeted pre-mRNA

Breast cancer

[99]

asFGFR2

Fine-tuning the chromatin structure to decrease the recruitment of the SF PTB

Breast cancer

[101]

HOXB-AS3

Encoding peptides to inhibit hnRNPA1-mediated AS

Colon cancer

[103]